Akkermansia Chewable Supplements: Health Benefits and Usage Guide
What Is Akkermansia Chewable?
Akkermansia chewable probiotics deliver the beneficial bacteria Akkermansia muciniphila directly into your digestive system in a tasty, convenient form. Known for supporting gut health, metabolism, and immunity, chewables like Next-Microbiome’s Probiome NOVO 2.0 Akkermansia Chewable are increasingly popular among those looking for gut microbiome chewable supplements and probiotics for metabolic and immune health.
Benefits of Akkermansia Chewable Probiotics
Strengthens Gut Barrier
Akkermansia improves gut lining integrity, reducing “leaky gut,” enhancing digestive comfort, and preventing toxins from entering your bloodstream.
📚 Everard et al., 2013
🔗 https://www.pnas.org/doi/10.1073/pnas.1219451110
Reduces Chronic Inflammation
Akkermansia chewables help lower inflammation by reducing harmful endotoxins like lipopolysaccharides (LPS), helping regulate immune responses effectively.
📚 Depommier et al., 2019
🔗 https://www.nature.com/articles/s41591-019-0495-2
Supports Metabolic Health
Higher abundance of Akkermansia muciniphila is linked to better metabolic health, stronger insulin sensitivity, and improved metabolic response during dietary intervention.
📚 Dao et al., 2016 — Human Study
🔗 https://pubmed.ncbi.nlm.nih.gov/26100928/
Supplementation studies also show improved glucose tolerance, reduced fat mass, and lower inflammation.
📚 Plovier et al., 2017
🔗 https://pubmed.ncbi.nlm.nih.gov/27821438/
Assists Weight Management
A major review published in Frontiers in Microbiology,
“Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila” (Cani et al., 2017), summarizes extensive evidence showing that A. muciniphila supports:
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fat-mass reduction
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metabolic flexibility
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improved insulin sensitivity
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reduced metabolic inflammation
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stronger gut barrier integrity
📚 Cani et al., 2017 — Review Article
🔗 https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2017.01765/full
Additional research supports improved glucose regulation and reduced adiposity.
📚 Greer et al., 2016
🔗 https://pmc.ncbi.nlm.nih.gov/articles/PMC5614963/
Oral Microbiome: Impact on Mood and Health
Oral–Gut–Brain Connection
The oral cavity contains the second most diverse microbial community in the human body. A comprehensive 2016 review,
“The Oral Microbiome: An Update for Oral Healthcare Professionals,”
explains how disruptions in the oral microbiome can influence gut microbes, systemic inflammation, and even neuroendocrine pathways that affect mood and cognition.
This emerging science supports the concept of an oral–gut–brain axis, meaning that optimizing oral microbial balance may benefit digestion, stress resilience, mental health, and overall wellbeing.
📚 Kilian et al., 2016
🔗 https://research.vu.nl/en/publications/the-oral-microbiome-an-update-for-oral-healthcare-professionals/
Additional evidence links oral dysbiosis to gut dysbiosis and systemic inflammation.
📚 Supporting Review
🔗 https://www.mdpi.com/2076-2607/13/4/814
Oral Health Benefits
Chewable probiotics work in the mouth before entering the gut, helping rebalance oral bacteria and reducing risk factors for gum disease, inflammation, and systemic conditions linked to oral dysbiosis.
📚 Kilian et al., 2016
🔗 https://research.vu.nl/en/publications/the-oral-microbiome-an-update-for-oral-healthcare-professionals/
Ingredients in Akkermansia Chewable
Probiotics (Lactobacillus, Bifidobacterium)
Support digestion, immunity, and inflammation balance.
Prebiotics (Inulin, HMOs)
Feed beneficial bacteria and increase microbiome diversity.
Vitamins (C, B12, Biotin)
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Vitamin C: immune & antioxidant support
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Vitamin B12: energy & nerve support
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Biotin: metabolic & skin health support
Collagen & Hyaluronic Acid
Improve skin hydration, firmness, and joint comfort.
Amino Acids (L-Theanine, Glutamine)
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L-Theanine: promotes calm, focus, and stress reduction
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Glutamine: supports gut lining integrity and immune health
Polyphenols (Resveratrol, Berry Extracts)
Antioxidants that support cardiovascular, cognitive, and cellular health.
Magnesium
Helps regulate sleep, muscle recovery, and stress response.
Why Choose Chewable Probiotics?
Chewables deliver:
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immediate oral microbiome benefits
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higher compliance
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better taste
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often better bacterial survival
They are ideal for anyone seeking a simple, enjoyable, and effective gut and oral microbiome routine.
Using Akkermansia Chewables
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Dosage: One chewable tablet daily (preferably at bedtime).
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Adjustment: Mild digestive changes may occur for 1–2 weeks.
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Optimal Results: Use consistently for 3–6 months.
User Reviews
Users frequently report:
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reduced bloating
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better digestion
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more stable energy
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improved mood
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enhanced metabolic comfort
Buy Akkermansia Chewable Supplements
Purchase Next-Microbiome Probiome NOVO 2.0 Akkermansia Chewable at:
👉 https://Akkermansia.life
Conclusion
Akkermansia chewable probiotics provide next-generation microbiome support rooted in strong scientific evidence. Unlike capsules, they work both in the oral microbiome and the gut microbiome, supporting:
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gut barrier integrity
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inflammation reduction
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metabolic regulation
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improved GLP-1 and insulin sensitivity
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healthier mood & stress resilience
Whether you're focused on digestion, immunity, metabolism, mood, or whole-body wellness, Akkermansia Chewables offer a comprehensive, scientifically grounded solution.
About the Author — Ali Rıza Akın
Microbiome Scientist • Author • Founder of Next-Microbiome
Ali Rıza Akın is a microbiome scientist with nearly 30 years of translational research and biotechnology experience. He is the discoverer of Christensenella californii, a beneficial human-associated bacterial species linked to metabolic and mucosal health.
His expertise includes:
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HPA axis & stress physiology
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cortisol regulation & circadian biology
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gut barrier & mucosal immunity
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SCFA & GLP-1 metabolic signaling
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oral–gut–brain axis communication
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next-generation synbiotic formulation
Ali is the author of Bakterin Kadar Yaşa: İçimizdeki Evren and a contributor to Bacterial Therapy of Cancer (Springer).
As Founder of Next-Microbiome, he develops advanced microbial formulations targeting:
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cortisol balance
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metabolic resilience
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sleep & circadian support
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gut barrier repair
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oral–gut–brain axis optimization
His mission is to translate cutting-edge microbiome science into accessible, effective daily health solutions.